Journal Title：Computational Biology And Chemistry

Computational Biology and Chemistry publishes original research papers and review articles in all areas of computational life sciences. High quality research contributions with a major computational component in the areas of nucleic acid and protein sequence research, molecular evolution, molecular genetics (functional genomics and proteomics), theory and practice of either biology-specific or chemical-biology-specific modeling, and structural biology of nucleic acids and proteins are particularly welcome. Exceptionally high quality research work in bioinformatics, systems biology, ecology, computational pharmacology, metabolism, biomedical engineering, epidemiology, and statistical genetics will also be considered.

Given their inherent uncertainty, protein modeling and molecular docking studies should be thoroughly validated. In the absence of experimental results for validation, the use of molecular dynamics simulations along with detailed free energy calculations, for example, should be used as complementary techniques to support the major conclusions. Submissions of premature modeling exercises without additional biological insights will not be considered.

Review articles will generally be commissioned by the editors and should not be submitted to the journal without explicit invitation. However prospective authors are welcome to send a brief (one to three pages) synopsis, which will be evaluated by the editors.

《計算生物學和化學》發(fā)表計算生命科學所有領域的原創(chuàng)研究論文和評論文章。特別歡迎在核酸和蛋白質(zhì)序列研究、分子進化、分子遺傳學（功能基因組學和蛋白質(zhì)組學）、生物特定或化學生物學特定建模的理論和實踐以及核酸和蛋白質(zhì)的結(jié)構(gòu)生物學等領域做出具有主要計算成分的高質(zhì)量研究貢獻。生物信息學、系統(tǒng)生物學、生態(tài)學、計算藥理學、代謝、生物醫(yī)學工程、流行病學和統(tǒng)計遺傳學領域的極高質(zhì)量研究工作也將受到考慮。

鑒于其固有的不確定性，應徹底驗證蛋白質(zhì)建模和分子對接研究。在沒有實驗結(jié)果進行驗證的情況下，應使用分子動力學模擬以及詳細的自由能計算等作為補充技術(shù)來支持主要結(jié)論。提交沒有額外生物學見解的過早建模練習將不予考慮。

評論文章通常由編輯委托撰寫，未經(jīng)明確邀請不得提交給期刊。但是，歡迎潛在作者發(fā)送簡短（一到三頁）的概要，編輯將對其進行評估。

Computational Biology And Chemistry創(chuàng)刊于2003年，由Elsevier Ltd出版商出版，收稿方向涵蓋生物 - 計算機：跨學科應用全領域，此期刊水平偏中等偏靠后，在所屬細分領域中專業(yè)影響力一般，過審相對較易，如果您文章質(zhì)量佳，選擇此期刊，發(fā)表機率較高。平均審稿速度 約15.0個月 ，影響因子指數(shù)2.6，該期刊近期沒有被列入國際期刊預警名單，廣大學者值得一試。